U.S. President Donald Trump on Tuesday called Iran the "most destructive force" in the Middle East, blaming Tehran for instability across the region and warning that the United States will never allow it to obtain a nuclear weapon.

President Donald Trump is holding out Saudi Arabia as a model for a reimagined Middle East. He's using his first major foreign trip of his term to emphasize the promise of economic prosperity over instability in a region that is reeling from multiple wars.

President Trump cherishes big, out-of-the-box deals. As he tours the region, Trump should think beyond Iran’s nuclear issue and work to achieve the denuclearization of the entire Middle East.

Iran said on Tuesday a recent round of talks with the U.S. had been fruitful but the imposition by Washington of further sanctions was not compatible with the negotiations.

DUBAI, United Arab Emirates (AP) — Iran and the United States held a fourth round of negotiations Sunday over Tehran’s rapidly advancing nuclear program, just ahead of a visit by President Donald Trump to the Middle East this week.

DUBAI (Reuters) - Recent U.S. sanctions on Iran are not constructive when it comes to negotiations, Iran's foreign ministry spokesperson Esmaeil Baghaei said on Tuesday, after the two countries held a fourth round of nuclear talks on Sunday in Oman.

Addis Ababa’s willingness to work with regional rivals in the Middle East shows its practical approach to foreign relations.

President Donald Trump turned to Iran and reiterated his stance against the nation if they don't come to a new deal with the U.S.