However, he decided to take a rest following the Roland Garros setback and recover for Queen's and Wimbledon. Musetti reached the Roland Garros semi-final and challenged the defending champion, Carlos Alcaraz.

Garros, No. 8 Lorenzo Musetti gave No. 2 Carlos Alcaraz all he could handle on Court Philippe-Chatrier, but the reigning French Open champion eventually settled in to take a 2-1 set lead before Musetti retired with a leg injury early in the fourth set to send Alcaraz to another final (4-6,